The Chicago White Sox are set to take on the Milwaukee Brewers on March 26, 2026, at 2:10 p.m. ET, marking the Opening Day of the Major League Baseball season. The game will take place at American Family Field in Milwaukee, Wisconsin, and will be available for streaming on Fubo, with coverage on Brewers.TV and the Chicago Sports Network.
Starting for the Brewers will be Jacob Misiorowski, while Shane Smith will take the mound for the White Sox. This matchup is particularly significant as both teams have contrasting aspirations for the season ahead.
The Brewers enter the 2026 season with playoff expectations, built around a strong foundation of elite pitching, solid defense, and timely offense. They are looking to capitalize on their strengths to secure a postseason berth.
In contrast, the White Sox are in a development and rebound phase following recent struggles. The team is focused on rebuilding and finding their footing in a competitive league.
Injury reports reveal that the Brewers will be without several key players, including Steward Berroa and Jackson Chourio, both on the 10 Day IL, as well as Rob Zastryzny, Craig Yoho, and Quinn Priester, who are on the 15 Day IL. Akil Baddoo is facing a longer recovery, listed on the 60 Day IL.
The White Sox also have notable absences, with Kyle Teel and Brooks Baldwin on the 10 Day IL, alongside Prelander Berroa, Drew Thorpe, Mike Vasil, and Ky Bush, who are all dealing with injuries.
As the game approaches, fans are eager to see how both teams will perform under pressure. The Brewers’ strong pitching lineup will be tested against the White Sox’s developing roster, making for an intriguing matchup.
Details remain unconfirmed regarding the final lineups as both teams finalize their rosters ahead of the game. Fans are hopeful for an exciting start to the MLB season, with both teams aiming to set the tone for their respective campaigns.
With the first pitch just hours away, anticipation is building in Milwaukee. The outcome of this game could set the stage for the season ahead for both the White Sox and the Brewers.